Anti-Smad1/5/9 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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SMAD1/SMAD5/SMAD9
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 ELISA: 1/10000
Immunogen
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Synthesized peptide derived from human Smad1/5/9.
Molecular Weight
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Calculated MW: 52 kDa; Observed MW: 52 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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4086/4090/4093
Uniprot ID
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Q15797/Q99717/O15198
Background
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Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
Research Area
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Signal Transduction
Synonyms
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Mothers against decapentaplegic homolog 1/5/9; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1/5/9; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein 1; BSP-1