Anti-SLUG Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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SNAI2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
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Recombinant Protein of SLUG
Molecular Weight
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Calculated MW: 30 kDa; Observed MW: 30 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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6591
Uniprot ID
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O43623
Background
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This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.
Research Area
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Neuroscience
Synonyms
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SNAI2; SLUG; SLUGH; Zinc finger protein SNAI2; Neural crest transcription factor Slug; Protein snail homolog 2