Anti-SIRP alpha Rabbit Monoclonal Antibody

Anti-SIRP alpha Rabbit Monoclonal Antibody
Anti-SIRP alpha Rabbit Monoclonal Antibody
Anti-SIRP alpha Rabbit Monoclonal Antibody
Anti-SIRP alpha Rabbit Monoclonal Antibody

Anti-SIRP alpha Rabbit Monoclonal Antibody

Rabbit IgG Monoclonal for SIRPA detection, Test with FC, ELISA in Human

Reactivity
  • Human
Application
  • FC
  • ELISA
Host
  • Rabbit
Catalog Number
    ABXB65021
$580.00

Shipping To:
United States

Product Information

Downloads & Supports

Target
    SIRPA
Host
  • Rabbit
Storage
    Store at -20°C to -80°C for 12 months in lyophilized form.
Clonality
  • Monoclonal
Clone Number
    R07-4M-2
Isotype
    IgG
Reactivity
  • Human
Application
  • FC
  • ELISA
Application Details
    FC: 1/50-1/100 ELISA: 1/10000
Immunogen
    Recombinant human SIRPα protein
Molecular Weight
    -
Formulation
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Form
    Lyophilized
Gene ID
    140885
Uniprot ID
    P78324
Background
    Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment.
Research Area
    Neuroscience
Synonyms
    SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP; Tyrosine-protein phosphatase non-receptor type substrate 1; SHP substrate 1; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs; Bit; CD172 antigen-like family member A; Inhibito
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Product Image

Flow Cytometry analysis of THP-1 cell line were surface stained with SIRPα antibody and Rabbit IgG isotype control antibody.
A. Flow Cytometry analysis of THP-1 cells stained with SIRP alpha antibody. The Yaxis represents the mean fluorescence intensity MFI while the Xaxis represents the concentration of IgG used. B. Competition assay demonstrating blockade of CD47 binding to THP-1 cells. IC50=30.88ng/ml.