Anti-Sialoadhesin/CD169 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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SIGLEC1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R09-1X-3
Isotype
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IgG
Reactivity
Application
Application Details
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IHC: 1/100-1/200
Immunogen
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A synthesized peptide derived from human CD169
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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6614
Uniprot ID
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Q9BZZ2
Background
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Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Plays a crucial role in limiting bacterial dissemination by engaging sialylated bacteria to promote effective phagocytosis and antigen presentation for the adaptive immune response (PubMed:12940982, PubMed:33489013).
Research Area
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Immunology
Synonyms
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SIGLEC1;SN;Sialoadhesin;Sialic acid-binding Ig-like lectin 1 (Siglec-1);CD169