Anti-SFRS15 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
-
SCAF4
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clonality
Clone Number
-
-
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/50-1/200
Immunogen
-
Synthetic peptide corresponding to Human SFRS15.
Molecular Weight
-
Calculated MW: 126kDa
Formulation
-
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Form
-
Liquid
Gene ID
-
57466
Uniprot ID
-
O95104
Background
-
The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domains. SFRS15 interacts with C-terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre-mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.
Research Area
-
-
Synonyms
-
Splicing factor, arginine/serine-rich 15; CTD-binding SR-like protein RA4; SR-related and CTD-associated factor 4; SCAF4; KIAA1172; SFRS15