Anti-SETD7 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
SETD7
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R09-7D-5
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IP: 1/20
Immunogen
-
Peptide
Molecular Weight
-
Calculated MW:41 kDa;Observed MW: 41,50 kDa
Formulation
-
Liquid in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Form
-
Liquid
Gene ID
-
80854
Uniprot ID
-
Q8WTS6
Background
-
Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription.
Research Area
-
Epigenetics and Nuclear Signaling
Synonyms
-
Histone H3-K4 methyltransferase SETD7; Lysine N-methyltransferase 7; SET domain-containing protein 7; SET7; SET9