Anti-SERCA1 ATPase Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ATP2A1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-2A3
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/50
Immunogen
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A synthesized peptide derived from human ATP2A1/SERCA1
Molecular Weight
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Calculated MW: 110 kDa; Observed MW: 100 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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487
Uniprot ID
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O14983
Background
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Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
Research Area
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Tags & Cell Markers
Synonyms
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ATP2A; ATP2A1; SERCA1