Anti-Septin 7 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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SEPTIN7
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Fusion protein of human SEPTIN7
Molecular Weight
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Calculated MW: 51 kDa; Observed MW: 51 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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989
Uniprot ID
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Q16181
Background
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Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830).
Research Area
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Tags & Cell Markers
Synonyms
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septin 7; CDC3; CDC10; SEPT7; SEPT7A; NBLA02942