Anti-SCOP Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
-
PHLPP1
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
-
IgG
Reactivity
Application
Application Details
-
IHC: 1/50-1/100
Immunogen
-
Fusion protein of human PHLPP1
Molecular Weight
-
-
Formulation
-
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
-
Liquid
Gene ID
-
23239
Uniprot ID
-
O60346
Background
-
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.
Research Area
-
Signal Transduction
Synonyms
-
PHLPP1