Anti-SCF Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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KITLG
Host
Storage
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Store at -20°C to -80°C for 12 months in lyophilized form.
Clonality
Clone Number
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R09-7O-1
Isotype
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IgG
Reactivity
Application
Application Details
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FC: 1/50-1/100 ELISA: 1/10000
Immunogen
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Recombinant human SCF protein
Molecular Weight
-
-
Formulation
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Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Form
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Lyophilized
Gene ID
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4254
Uniprot ID
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P21583
Background
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Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1.
Research Area
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Immunology
Synonyms
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SF; SCF; MGF; FPH2; KL-1; Kitl