Anti-S100 beta Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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S100B
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R09-7K-9
Isotype
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IgG
Reactivity
Application
Application Details
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IHC-P：1/50-1/100
Immunogen
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Peptide
Molecular Weight
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Calculated MW: 11 kDa; Observed MW:11 kDa
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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6285
Uniprot ID
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P04271
Background
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Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Research Area
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Cell Biology
Synonyms
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S100 beta