Anti-RUNX2 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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RUNX2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-3D-7
Isotype
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IgG
Reactivity
Application
Application Details
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IHC: 1/100-1/200
Immunogen
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Recombinant protein of human RUNX2
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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860
Uniprot ID
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Q13950
Background
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RUNX2 regulates the transcription of various genes, including osteopontin, bone sialoprotein, and osteocalcin, via binding to the core site of the enhancers or promoters. RUNX2 is crucial for the maturation of osteoblasts and both intramembranous and endochondral ossification.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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RUNX2; AML3; CBFA1; OSF2; PEBP2A; Runt-related transcription factor 2; Acute myeloid leukemia 3 protein; Core-binding factor subunit alpha-1; CBF-alpha-1; Oncogene AML-3; Osteoblast-specific transcription factor 2; OSF-2; Polyomavirus enhan