Anti-RUNX Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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RUNX1/RUNX2/RUNX3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-7I9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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A synthetic peptide of human RUNX1/2/3
Molecular Weight
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Calculated MW: 49 kDa; Observed MW: 49 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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861/864/860
Uniprot ID
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Q01196/Q13761/Q13950
Background
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RUNX2 regulates the transcription of various genes including osteopontin, bone sialoprotein, and osteocalcin via binding to the core site of the enhancers or promoters.RUNX3/AML2 is a member of the Runt family of transcription factors. RUNX3 is important for the suppression of cell proliferation in the gastric epithelium, neurogenesis of the dorsal root ganglia, and T cell differentiation.
Research Area
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Neuroscience
Synonyms
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RUNX1; AML1; RUNX2; OSF2; RUNX3; CBFA3