Anti-RPE65 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
RPE65
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R07-1E1
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IP: 1/50
Immunogen
-
A synthesized peptide derived from human RPE65
Molecular Weight
-
Calculated MW: 61 kDa; Observed MW: 61 kDa
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
6121
Uniprot ID
-
Q16518
Background
-
Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol.
Research Area
-
Tags & Cell Markers
Synonyms
-
LCA2; mRPE65; p63; rd12; Retinal pigment epithelium specific 61 kDa protein; RP20; RPE65; sRPE65