Anti-RNase L Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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RNASEL
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R04-2P2
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthesized peptide derived from human RNase L
Molecular Weight
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Calculated MW: 84 kDa; Observed MW: 80 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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6041
Uniprot ID
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Q05823
Background
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Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes.
Research Area
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Immunology
Synonyms
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PRCA1; Ribonuclease4; RibonucleaseL; RNase L; Rnasel; RNS4