Anti-RIP Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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Ripk1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-4Z-8
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Immunogen
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Recombinant protein
Molecular Weight
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Calculated MW:75 kDa;Observed MW: 75 kDa
Formulation
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Liquid in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Form
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Liquid
Gene ID
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19766
Uniprot ID
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Q60855
Background
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Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade (By similarity).Required for ZBP1-induced NF-kappa-B activation in response to DNA damage (PubMed:12654725, PubMed:19590578).
Research Area
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Cell Biology
Synonyms
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Ripk1,Rinp,Rip,Rinp, Rip,Receptor-interacting serine/threonine-protein kinase 1,Cell death protein RIP,Receptor-interacting protein 1