Anti-RIP Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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RIPK1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R08-9K5
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Recombinant protein of human RIP
Molecular Weight
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Calculated MW: 76 kDa; Observed MW: 76 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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8737
Uniprot ID
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Q13546
Background
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Essential adapter molecule for the activation of NF-kappa-B. Following different upstream signals (binding of inflammatory cytokines, stimulation of pathogen recognition receptors, or DNA damage), particular RIPK1-containing complexes are formed, initiating a limited number of cellular responses.
Research Area
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Cell Biology
Synonyms
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RIPK1; Cell death protein RIP; RIP1; RIP; RIP-1; Rinp