Anti-RING2 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
-
RNF2
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
-
A synthesized peptide derived from human RING2 / RING1B / RNF2
Molecular Weight
-
Calculated MW: 38 kDa; Observed MW: 38 kDa
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
6045
Uniprot ID
-
Q99496
Background
-
E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.
Research Area
-
Epigenetics and Nuclear Signaling
Synonyms
-
BAP1; DING; BAP-1; HIPI3; RING2; RING1B