Anti-RES Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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REST
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Synthetic peptide of human REST
Molecular Weight
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Calculated MW: 122 kDa; Observed MW: 122 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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5978
Uniprot ID
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Q13127
Background
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Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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NRSF; RE1 silencing transcription factor; Repressor binding to the X2 box; rest; X2 box repressor; XBR