Anti-RASSF1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
RASSF1
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R32-5W-8
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/100-1/200
Immunogen
-
A synthesized peptide derived from human RASSF1
Molecular Weight
-
Calculated MW: 39 kDa;Observed MW:39kDa
Formulation
-
Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
11186
Uniprot ID
-
Q9NS23
Background
-
Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.
Research Area
-
Cell Biology
Synonyms
-
NORE2A;