Anti-Ras(G12D Mutant) Mouse Monoclonal Antibody

Anti-Ras(G12D Mutant) Mouse Monoclonal Antibody
Anti-Ras(G12D Mutant) Mouse Monoclonal Antibody

Anti-Ras(G12D Mutant) Mouse Monoclonal Antibody

Mouse IgG1,IgG2a,IgG2b Monoclonal for RAS(G12D) detection, Test with WB, IHC-P, ICC/IF, ELISA in Vertebrates

Reactivity
  • Vertebrates
Application
  • WB
  • IHC-P
  • ICC
  • IF
  • ELISA
Host
  • Mouse
Catalog Number
    ABXB07378
$680.00

Shipping To:
United States

Product Information

Downloads & Supports

Target
    RAS(G12D)
Host
  • Mouse
Storage
    Store at -20°C. Avoid repeated freezing and thawing
Clonality
  • Monoclonal
Clone Number
    7D8-P1-Y1
Isotype
    IgG1,IgG2a,IgG2b
Reactivity
  • Vertebrates
Application
  • WB
  • IHC-P
  • ICC
  • IF
  • ELISA
Application Details
    WB:1/100-1/1000；ICC/IF: 1/50-1/100；IHC-P: 1/50-1/100；ELISA: 1/100-1/3000
Immunogen
    A synthetic peptide from the internal region of Ras which includes the mutation of G12D, human origin
Formulation
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Form
    Liquid
Uniprot ID
    ­
Background
    Ras (G12D) is one type of Ras missense mutations at the codon 12. Ras protein is a membrane-associated GTPase that regulates cell proliferation, differentiation, and survival. Ras G12D mutation results in decreased GTPase activity and constitutive signaling. This mutation is found in many types of human cancers.
Research Area
    Signal Transduction
Synonyms
    RAS(G12D)
MSDSProtocolsRequest COAAlgent Product GuaranteeNeed support?

Product Image

Western blot analysis of recombinant Ras WT and G12D proteins. Equal amounts of purified Ras WT (lane 1) and G12D (lane 2) proteins were loaded and blotted with anti-Ras G12D mouse monoclonal (Top panel). Input control (bottom panel) was blotted with rabbit polyclonal anti-Ras.