Anti-RAPGEF1 Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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RAPGEF1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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ZN140
Isotype
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IgG1
Reactivity
Application
Application Details
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IHC: 1/50-1/100
Immunogen
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Full length human recombinant protein of human RAPGEF1(NP_941372) produced in HEK293T cell.
Molecular Weight
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-
Formulation
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PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Form
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Liquid
Gene ID
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2889
Uniprot ID
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Q13905
Background
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This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Research Area
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Signal Transduction
Synonyms
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C3G; GRF2；Rap guanine nucleotide exchange factor 1；RAPGEF1；Protein C3G；Guanine nucleotide-releasing factor 2；CRK SH3-binding GNRP