Anti-RALBP1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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RALBP1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R02-2K6
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human RALBP1
Molecular Weight
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Calculated MW: 76 kDa; Observed MW: 95 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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10928
Uniprot ID
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Q15311
Background
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RalBP1 interacts with RalA and the endocytosis protein REPS2 (POB1) through its carboxy-terminal Ral binding domain. RalBP1 has an intrinsic GTPase activating function and interacts with Cdc42 through its centrally located Rho-GAP domain. A protein complex containing RalBP1/POB1/RalA regulates endocytosis of membrane receptors. RalBP1 also functions as a non-ABC transporter that catalyzes the ATP-dependent transport of numerous xenobiotics, including glutathione conjugates and some chemotherapeutic agents.
Research Area
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Cell Biology
Synonyms
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RALBP1; RIP1; RLIP1; RLIP76