Anti-Rad50 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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RAD50
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R05-5H6
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthetic peptide of human Rad50
Molecular Weight
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Calculated MW: 154 kDa; Observed MW: 154 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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10111
Uniprot ID
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Q92878
Background
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Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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RAD50; DNA repair protein RAD50; hRAD50