Anti-Rac3 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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RAC3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Full length fusion protein
Molecular Weight
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Calculated MW: 21 kDa; Observed MW: 21 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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5881
Uniprot ID
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P60763
Background
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Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.
Research Area
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Signal Transduction
Synonyms
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ras-related C3 botulinum toxin substrate 3 (rho family; small GTP binding protein Rac3)