Anti-RAB35 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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RAB35
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clonality
Clone Number
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Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Synthetic peptide corresponding to Human RAB35.
Molecular Weight
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Calculated MW: 23kDa
Formulation
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1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Form
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Liquid
Gene ID
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11021
Uniprot ID
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Q15286
Background
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The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, all of which are thought to play an important role in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab 35, also known as Rab 1C or RAY, is a 201 amino acid lipidanchored protein that is thought to function as a GTPase, playing a role in exocytotic and endocytotic pathways and functioning as an important factor in cytokinesis. Rab 35 is expressed ubiquitously and is encoded by a gene that maps to human chromosome 12, which houses over 1,100 genes and comprises approximately 4.5% of the human genome.
Research Area
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Synonyms
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Ras-related protein Rab-35; GTP-binding protein RAY; Ras-related protein Rab-1C; RAB1C; RAY