Anti-PU.1/SPI1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
SPI1
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R01-9Y-9
Isotype
-
IgG
Reactivity
Application
Application Details
-
IHC: 1/100-1/200
Immunogen
-
A synthesized peptide derived from human PU.1
Formulation
-
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
-
Liquid
Gene ID
-
6688
Uniprot ID
-
P17947
Background
-
Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.
Research Area
-
Immunology
Synonyms
-
SPI1; Transcription factor PU.1; 31 kDa-transforming protein