Anti-PTPN22 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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PTPN22
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Fusion protein of human PTPN22
Molecular Weight
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Calculated MW: 92 kDa; Observed MW: 92 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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26191
Uniprot ID
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Q9Y2R2
Background
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Acts as negative regulator of T-cell receptor (TCR) signaling by direct dephosphorylation of the Src family kinases LCK and FYN, ITAMs of the TCRz/CD3 complex, as well as ZAP70, VAV, VCP and other key signaling molecules.
Research Area
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Signal Transduction
Synonyms
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LYP; PEP; LYP1; LYP2; PTPN8