Anti-Proteasome alpha 6 Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
PSMA6
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
ZN102
Isotype
-
IgG1
Reactivity
Application
Application Details
-
IHC: 1/50-1/100
Immunogen
-
Full length human recombinant protein of human PSMA6 (NP_002782) produced in E.coli.
Molecular Weight
-
-
Formulation
-
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Form
-
Liquid
Gene ID
-
5687
Uniprot ID
-
P60900
Background
-
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Jul 2008]
Research Area
-
Cell Biology
Synonyms
-
PSMA6; proteasome subunit alpha 6;p27K; PROS27