Anti-Prostate Specific Antigen Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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KLK3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R05-5H2
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human PSA/KLK3
Molecular Weight
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Calculated MW: 29 kDa; Observed MW: 34 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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354
Uniprot ID
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P07288
Background
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PSA/KLK3 is a member of the glandular kallikrein subfamily of serine proteases. Upon cleavage of 7 amino-terminal amino acids, it is activated to liquefy semen in the seminal coagulum. Although PSA/KLK3 is produced in healthy individuals, investigators have found abnormally high levels in the blood of men with advanced prostate cancer.
Research Area
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Neuroscience
Synonyms
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KLK3; APS; Prostate-specific antigen; PSA; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase