Anti-Prostate Specific Antigen Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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KLK3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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4B3-10G7-9B8
Isotype
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IgG1
Reactivity
Application
Application Details
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IHC: 1/100-1/500
Immunogen
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Synthesized peptide derived from human Prostate-Specific Antigen(PSA)
Molecular Weight
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-
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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354
Uniprot ID
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P07288
Background
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PSA/KLK3 is a member of the glandular kallikrein subfamily of serine proteases. Upon cleavage of 7 amino-terminal amino acids, it is activated to liquefy semen in the seminal coagulum. Although PSA/KLK3 is produced in healthy individuals, investigators have found abnormally high levels in the blood of men with advanced prostate cancer.
Research Area
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Neuroscience
Synonyms
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KLK3; APS; Prostate-specific antigen; PSA; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase