Anti-PRDM1/Blimp1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PRDM1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-5B-4
Isotype
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IgG
Reactivity
Application
Application Details
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IHC: 1/100-1/200
Immunogen
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Recombinant protein of human PRDM1
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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639
Uniprot ID
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O75626
Background
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Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection (By similarity).
Research Area
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Immunology
Synonyms
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PRDM1;BLIMP1;PR domain zinc finger protein 1;BLIMP-1;Beta-interferon gene positive regulatory domain I-binding factor;PR domain-containing protein 1;Positive regulatory domain I-binding factor 1 (PRDI-BF1; PRDI-binding factor 1)