Anti-PPM1G Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PPM1G
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R05-8C4
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Recombinant protein of human PPM1G
Molecular Weight
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Calculated MW: 59 kDa; Observed MW: 75 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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5496
Uniprot ID
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O15355
Background
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The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
Research Area
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Cell Biology
Synonyms
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Protein phosphatase 1G; PP2C-gamma; Protein phosphatase magnesium-dependent 1 gamma