Anti-Poliovirus Receptor Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PVR
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R01-8A1
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Recombinant protein of human Poliovirus Receptor/PVR
Molecular Weight
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Calculated MW: 45 kDa; Observed MW: 60-80 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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5817
Uniprot ID
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P15151
Background
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Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell.
Research Area
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Immunology
Synonyms
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PVR; PVS; Poliovirus receptor; Nectin-like protein 5; NECL-5; CD155