Anti-PKR Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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Eif2Ak2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R04-3F2
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Immunogen
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Recombinant protein of mouse PKR
Molecular Weight
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Calculated MW: 58 kDa; Observed MW: 74 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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19106
Uniprot ID
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Q03963
Background
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IFN-induced dsRNA-dependent serine/threonine-protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) and plays a key role in the innate immune response to viral infection.
Research Area
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Signal Transduction
Synonyms
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PKR; PRKR; EIF2AK1; PPP1R83