Anti-PKR Rabbit Monoclonal Antibody

Anti-PKR Rabbit Monoclonal Antibody
Anti-PKR Rabbit Monoclonal Antibody
Anti-PKR Rabbit Monoclonal Antibody
Anti-PKR Rabbit Monoclonal Antibody
Anti-PKR Rabbit Monoclonal Antibody
Anti-PKR Rabbit Monoclonal Antibody

Anti-PKR Rabbit Monoclonal Antibody

Rabbit IgG Monoclonal for EIF2AK2 detection, Test with WB, IHC-F, IHC-P, ICC/IF, IP in Human

Reactivity
  • Human
Application
  • WB
  • IHC-F
  • IHC-P
  • ICC
  • IF
  • IP
Host
  • Rabbit
Catalog Number
    ABXB60411
$370.00

Shipping To:
United States

Product Information

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Target
    EIF2AK2
Host
  • Rabbit
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    R08-2C8
Isotype
    IgG
Reactivity
  • Human
Application
  • WB
  • IHC-F
  • IHC-P
  • ICC
  • IF
  • IP
Application Details
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Immunogen
    A synthetic peptide of human PKR
Molecular Weight
    Calculated MW: 62 kDa; Observed MW: 74 kDa
Formulation
    50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
    Liquid
Gene ID
    5610
Uniprot ID
    P19525
Background
    PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.
Research Area
    Signal Transduction
Synonyms
    EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
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Product Image

Western blot analysis of PKR in K562, Hela lysates using PKR antibody.
Immunocytochemistry analysis of PKR(green) in Hela using PKR antibody,and DAPI(blue)
Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using PKR antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.