Anti-PKM2 (1F2) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PKM
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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1F2-F4-H11
Isotype
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IgG2b
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Immunogen
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Purified recombinant human PKM2 protein fragments expressed in E.coli.
Molecular Weight
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Calculated MW: 58 kDa; Observed MW: 58 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.02% sodium azide, pH 7.4.
Form
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Liquid
Gene ID
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5315
Uniprot ID
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P14618
Background
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Pyruvate kinase is a glycolytic enzyme that catalyses the conversion of phosphoenolpyruvate to pyruvate. PKM2 is shown to be essential for aerobic glycolysis in tumors, known as the Warburg effect.
Research Area
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Signal Transduction
Synonyms
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PKM; OIP3; PK2; PK3; PKM2; Pyruvate kinase isozymes M1/M2; Cytosolic thyroid hormone-binding protein; CTHBP; Opa-interacting protein 3; OIP-3; Pyruvate kinase 2/3; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; THBP1; Tu