Anti-PKC zeta Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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PRKCZ
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Immunogen
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The antiserum was produced against synthesized peptide derived from human PKC zeta.
Molecular Weight
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Calculated MW: 68 kDa; Observed MW: 80 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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5590
Uniprot ID
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Q05513
Background
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PKC is one of the earliest events in a cascade that controls a variety of cellular responses, including secretion, gene expression, proliferation, and muscle contraction. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.
Research Area
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Signal Transduction
Synonyms
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PRKCZ; PKC2; Protein kinase C zeta type; nPKC-zeta