Anti-PIWIL1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PIWIL1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R07-3U9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthesized peptide derived from human PIWIL1
Molecular Weight
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Calculated MW: 99 kDa; Observed MW: 99 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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9271
Uniprot ID
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Q96J94
Background
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Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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HIWI; MIWI; PIWI; PIWIL1