Anti-PIM2 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PIM2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R09-8B6
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/50
Immunogen
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A synthesized peptide derived from human PIM2
Molecular Weight
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Calculated MW: 34 kDa; Observed MW: 37 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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11040
Uniprot ID
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Q9P1W9
Background
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Promotes cell survival in response to a variety of proliferative signals via positive regulation of the I-kappaB kinase/NF-kappaB cascade; this process requires phosphorylation of MAP3K8/COT. Prevents apoptosis induced by growth factor withdrawal via inhibition of caspase-3 activation, and via phosphorylation of pro-apoptotic proteins.
Research Area
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Signal Transduction
Synonyms
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PIM2; Serine/threonine-protein kinase pim-2; Pim-2h