Anti-PIK3CA(Q546P Mutant) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha
Host
Storage
-
Store at -20°C. Avoid repeated freezing and thawing
Clonality
Clone Number
-
7I9-T6-P3
Isotype
-
IgG
Reactivity
Application
Application Details
-
ELISA: 1/1000-1/5000 WB: 1/500-1/2000
Immunogen
-
A synthetic peptide from the internal region of PIK3CA which includes the mutation of Q546P, human origin.
Formulation
-
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Form
-
Liquid
Uniprot ID
-
Background
-
Phosphatidyl 3-kinases (PI3K) are a family of lipid kinases involved in many cellular processes, including cell growth, proliferation, differentiation, motility, and survival. It is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. Mutants of PIK3CA has been found in the pathogenesis of several cancers, including colon cancer, gliomas, gastric cancer, breast cancer, endometrial cancer, and lung cancer.
Research Area
-
Signal Transduction
Synonyms
-
PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha