Anti-PIAS2 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PIAS2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-4T8
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200
Immunogen
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A synthesized peptide derived from human PIAS2
Molecular Weight
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Calculated MW: 68 kDa; Observed MW: 55 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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9063
Uniprot ID
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O75928
Background
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Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulator in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway.
Research Area
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Synonyms
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DIP; MIZ; MIZ1; SIZ2; ARIP3; PIASX; ZMIZ4; PIASX-BETA; PIASX-ALPHA