Anti-PI3 Kinase p55 gamma Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
PIK3R3
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R08-4G4
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
-
A synthesized peptide derived from human PI 3 Kinase p55 gamma
Molecular Weight
-
Calculated MW: 54 kDa; Observed MW: 54 kDa
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
8503
Uniprot ID
-
Q92569
Background
-
Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle.
Research Area
-
Signal Transduction
Synonyms
-
GRB1; P85A; PI3-kinase p85-alpha subunit; PI3K; PI3K p85-alpha; P55G; PI3-kinase p85-gamma subunit; PI3K p85-gamma