Anti-Phospho-YAP1 (Ser127) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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YAP1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R07-6C2
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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A synthetic phosphopeptide corresponding to residues surrounding Ser127 of human YAP1
Molecular Weight
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Calculated MW: 54 kDa; Observed MW: 70-75 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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10413
Uniprot ID
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P46937
Background
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YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
Research Area
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Signal Transduction
Synonyms
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YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65