Anti-Phospho-XIAP (Ser87) Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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XIAP
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Synthetic peptide of human XIAP
Molecular Weight
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Calculated MW: 57 kDa; Observed MW: 57 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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331
Uniprot ID
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P98170
Background
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This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme.
Research Area
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Cell Biology
Synonyms
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API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3