Anti-Phospho-VASP (Ser157) Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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VASP
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Peptide sequence around phosphorylation site of serine 157 (R-V-S(p)-N-A) derived from Human VASP.
Molecular Weight
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Calculated MW: 40 kDa; Observed MW: 50 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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7408
Uniprot ID
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P50552
Background
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VASP (vasodilator-stimulated phosphoprotein), is involved in the maintenance of cytoarchitecture by interacting with actin-like filaments. VASP shares a limited degree of homology with the amino terminus of WASP, which is frequently mutated in WAS patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane.
Research Area
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Signal Transduction
Synonyms
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Vasodilator-stimulated phosphoprotein