Anti-Phospho-TAOK1/2/3 (Ser181 + Ser181 + Ser177) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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TAOK1/TAOK2/TAOK3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R32-3H-4
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/100-1/200
Immunogen
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A synthesized peptide derived from human Phospho-TAOK1/2/3 (S181 + S181 + S177)
Molecular Weight
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Calculated MW: 116 kDa;Observed MW:140,130,110kDa
Formulation
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Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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51347/57551/9344
Uniprot ID
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Q7L7X3/Q9UL54/Q9H2K8
Background
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Serine/threonine-protein kinase involved in different processes such as membrane blebbing and apoptotic bodies formation DNA damage response and MAPK14/p38 MAPK stress-activated MAPK cascade. Phosphorylates itself, MBP, activated MAPK8, MAP2K3, MAP2K6 and tubulins. Activates the MAPK14/p38 MAPK signaling pathway through the specific activation and phosphorylation of the upstream MAP2K3 and MAP2K6 kinases.
Research Area
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Signal Transduction
Synonyms
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TAOK1; TAOK2; TAOK3;