Anti-Phospho-Syk (Tyr348) Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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SYK
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Immunogen
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Synthetic peptide of human SYK
Molecular Weight
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Calculated MW: 72 kDa; Observed MW: 72 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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6850
Uniprot ID
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P43405
Background
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This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Area
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Cardiovascular
Synonyms
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SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk