Anti-Phospho-PKC zeta (Thr560) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PRKCZ
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-9T9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human PKC zeta
Molecular Weight
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Calculated MW: 68 kDa; Observed MW: 68 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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5590
Uniprot ID
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Q05513
Background
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PKC is one of the earliest events in a cascade that controls a variety of cellular responses, including secretion, gene expression, proliferation, and muscle contraction. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.
Research Area
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Signal Transduction
Synonyms
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PRKCZ; PKC2; Protein kinase C zeta type; nPKC-zeta