Anti-Phospho-PHB (Tyr259) Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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PHB1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Synthetic peptide of human PHB1
Molecular Weight
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Calculated MW: 30 kDa; Observed MW: 30 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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5245
Uniprot ID
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P35232
Background
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PHB1 is 30kDa tumor suppressor protein involved in cell cycle control. PHB1 has been found in mitochondria, the nucleus and the plasma membrane, as well as extracellularly in circulation. In mitochondria prohibitins mainly exist as membrane-bound ring complexes and function as chaperones maintaining mitochondrial protein stability during protein synthesis and transportation.
Research Area
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Cell Biology
Synonyms
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PHB1; HEL-215; HEL-S-54e